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Enrofloxacin — veterinary medicines

Authorised animal medicines containing Enrofloxacin across national registers. Regulatory residue limits (MRL) and antimicrobial-resistance surveillance are shown when on record. This is a neutral reference and does not provide dosing or veterinary advice.
Reference information only — not veterinary advice and not a dosing source. Always consult a licensed veterinarian before giving any medicine to an animal.

Target species

Dog or catDogsCatsPoultryCattleSwine (pigs)GoatsPigsSheepOrnamental BirdsRabbitsReptilesRodentsExotic AnimalChickensTurkeys

Authorised products

159 authorised products across national registers.

United Kingdom — VMD

Residue limits (MRL)

Species: All other food producing species

100 μg/kg

European Union

Species: All other food producing species · Tissue: Fat

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: All other food producing species

200 μg/kg

European Union

Species: All other food producing species · Tissue: Kidney

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: All other food producing species

200 μg/kg

European Union

Species: All other food producing species · Tissue: Liver

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: All other food producing species

100 μg/kg

European Union

Species: All other food producing species · Tissue: Muscle

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Bovine, ovine, caprine

100 μg/kg

European Union

Species: Bovine, ovine, caprine · Tissue: Fat

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Bovine, ovine, caprine

200 μg/kg

European Union

Species: Bovine, ovine, caprine · Tissue: Kidney

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Bovine, ovine, caprine

300 μg/kg

European Union

Species: Bovine, ovine, caprine · Tissue: Liver

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Bovine, ovine, caprine

100 μg/kg

European Union

Species: Bovine, ovine, caprine · Tissue: Milk

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Bovine, ovine, caprine

100 μg/kg

European Union

Species: Bovine, ovine, caprine · Tissue: Muscle

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Cattle

0.1 ppm

United States

Species: Cattle · Tissue: Liver (target tissue)

Species: Porcine, rabbit

100 μg/kg

European Union

Species: Porcine, rabbit · Tissue: Fat

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Porcine, rabbit

300 μg/kg

European Union

Species: Porcine, rabbit · Tissue: Kidney

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Porcine, rabbit

200 μg/kg

European Union

Species: Porcine, rabbit · Tissue: Liver

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Porcine, rabbit

100 μg/kg

European Union

Species: Porcine, rabbit · Tissue: Muscle

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Poultry

300 μg/kg

European Union

Species: Poultry · Tissue: Kidney

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Poultry

200 μg/kg

European Union

Species: Poultry · Tissue: Liver

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Poultry

100 μg/kg

European Union

Species: Poultry · Tissue: Muscle

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Poultry

100 μg/kg

European Union

Species: Poultry · Tissue: Skin and fat

Marker residue: Sum of enrofloxacin and ciprofloxacin

Therapeutic class: Anti-infectious agents/Antibiotics

Species: Swine

0.5 ppm

United States

Species: Swine · Tissue: Liver (target tissue)

Antimicrobial resistance surveillance

E. coli · Dogs

Enrofloxacin

NARMS

Resistant: 15.7% · 1121/7154 resistant

Year: 2017–2021

Klebsiella spp · Dogs

Enrofloxacin

NARMS

Resistant: 23% · 52/226 resistant

Year: 2019–2021

S. pseudintermedius · Dogs

Enrofloxacin

NARMS

Resistant: 39.5% · 2951/7472 resistant

Year: 2017–2021

Salmonella · Dogs

Enrofloxacin

NARMS

Resistant: 10.8% · 13/120 resistant

Year: 2017–2021

Reported adverse events (openFDA)

Spontaneous adverse-event reports that name Enrofloxacin, by species — reported counts, not proven reactions.

Dog

3,707 reported events

openFDA

Top reactions: Vomiting (816) · Lethargy (see also Central nervous system depression in 'Neurological') (496) · Anorexia (427) · Death by euthanasia (397) · Other abnormal test result NOS (348)

Cat

1,594 reported events

openFDA

Top reactions: Mydriasis (454) · Blindness (400) · Retinal disorder NOS (244) · Death by euthanasia (163) · Anorexia (153)

Cattle

232 reported events

openFDA

Top reactions: Death (105) · Lack of efficacy (bacteria) - NOS (46) · Lack of efficacy - NOS (46) · Respiratory tract disorder NOS (21) · Depression (15)

Horse

73 reported events

openFDA

Top reactions: Death (10) · Death by euthanasia (9) · Ataxia (8) · Diarrhoea (7) · Shaking (6)

Source: openFDA Animal & Veterinary adverse-event reports.

Surveillance reference only — these are spontaneous adverse-event report counts, not proven adverse reactions, not causation and not a measure of any product's risk or safety. Always consult a licensed veterinarian.

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